Xanax Addiction

Xanax is a benzodiazepine medication. This is a prescription medicine designed for short-term treatment of anxiety disorders, panic attacks, anxiety associated with depression, and some other off-label treatments related to panic.

The drug can be prescribed in the form of immediate-release (IR) and extended-release (XR) tablets, a liquid, and disintegrating tablets. The brand name was developed by Pfizer and approved for prescription use by the Food and Drug Administration (FDA) in 1981. Now, this benzodiazepine is also available in its generic form, alprazolam.

The History of Benzodiazepines and the Creation of Xanax

Benzodiazepines as a drug class were discovered in the 1930s, but the first prescription version of these substances was not introduced until 1957 when Librium was first approved to treat anxiety. These medications were created as a safer, less potentially addictive alternative to barbiturates, the main sedative at the time, which was widely abused.

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When benzodiazepines were first introduced, however, they were prescribed for the long-term, which also led to high rates of drug abuse.

Prescription misuse occurred when the dose was changed, or the prescription was mixed with other drugs, especially alcohol. Now, there are safer prescribing practices for benzodiazepines, but because they still are widely prescribed, they may be widely misused or abused.

There are more than 2,000 types of benzodiazepines, though few of the specific chemicals are approved for prescription use.

woman synthesizing xanax in a lab

These chemicals can cause quick intoxication and dangerous side effects. These chemicals are also responsible for the highly addictive nature of benzodiazepines.

There are three general categories of benzodiazepines: ultra-short, short, and long-acting.

  • Ultra-short acting benzodiazepines: Halcion/Versed
  • Short-acting benzodiazepines: Xanax/Ativan
  • Long-acting benzodiazepines: Valium/Librium

Xanax is one of the most prescribed benzodiazepine medications in the U.S., alongside Valium, Klonopin, and Ativan. All benzodiazepine medications act on the gamma-aminobutyric acid (GABA) receptors, which regulate how much of the GABA neurotransmitter is active in the brain. By binding to these receptors, benzodiazepines allow the GABA neurotransmitter to remain effective for longer, which can induce a sense of calm, pleasant relaxation, and even sleepiness. This is because Xanax, like other benzodiazepines and related sedatives, is a central nervous system (CNS) depressant.

Standard dose sizes of Xanax are 0.25, 0.5, 1, or 2 milligrams (mg); to achieve this dose, the user may take one or two tablets, or cut a tablet in half. How a person takes Xanax involves a conversation between them and their prescribing physician.

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  • Peak concentrations of Xanax in the body occur within one to two hours after the medication is taken. Effects begin to wear off after that, but some metabolites of the drug will remain active in the body. The elimination half-life for alprazolam, according to the FDA, is 11.2 hours in adults, so the drug is fully out of the body within a day.

    The GABA receptors are a group of neurons associated with the brain’s reward system. By triggering these receptors artificially, other parts of the reward system may become activated, leading to the release of other neurotransmitters like dopamine and serotonin, which are associated with elevated mood. When a substance quickly stimulates the reward system, compulsive behaviors and cravings can develop, and the person may begin abusing the substance to feel good or normal. According to the FDA, compulsive behaviors and physical dependence occur, on average, in people treated with doses of 4 mg or more per day consistently for 12 weeks or longer.

    Xanax and other benzodiazepines are widely abused for their similar effects to alcohol. Both substances impact the GABA receptors, leading to sedation, sleepiness, dizziness, and a high that can change reaction times and physical control. The pleasant feeling associated with both alcohol and Xanax can trigger compulsive behaviors in some people.

    In addition to appearing intoxicated, there are more signs of addiction to Xanax, which include:

    • Lying about how much is taken/denying
    • Obsessing over the drug
    • Paraphernalia
    • Consistently running out of the prescription too soon
    • Doctor shopping
    • Increased tolerance to the drug
    • Inability to quit taking the medication

    The 2014 National Survey on Drug Use and Health (NSDUH) found that, on average, 1.5 million Americans started using tranquilizers and sedatives, including Xanax, nonmedically every year. Physicians are not recommended to prescribe more than 4 mg per day of Xanax, and even that is excessive for most people. People who abuse Xanax may take anywhere from 8 mg to 20 mg per day, often combining this substance with other recreational substances–most often, alcohol, opioids, and cocaine.

    A report from the Substance Abuse and Mental Health Services Administration (SAMHSA) found that benzodiazepines like Xanax increase the intoxicating effects of other sedatives, especially opioids and alcohol. Between 2005 and 2011, according to the report, there were close to 1 million emergency room (ER) admissions involving benzodiazepines, either alone or in combination with other substances: 89,310 admissions were from benzodiazepines alone; 50,561 involved benzodiazepines and opioids; 27,452 admissions involved benzodiazepines and alcohol; and 8,229 admissions involved benzodiazepines, alcohol, and opioids together. Adding benzodiazepines to other forms of substance abuse radically increased the risk of long-term hospitalization and serious complications.

    XANAX ABUSE SHOULDN’T BE HANDLED ALONE – WE’RE HERE TO HELP.

    XANAX ABUSE SHOULDN’T BE HANDLED ALONE – WE’RE HERE TO HELP.

    Short-Term and Long-Term Dangers

    When abused on a short-term basis, Xanax can lead to side effects, such as:

    • Lightheadedness
    • Drowsiness
    • Fatigue and lethargy
    • Impaired coordination as though drunk
    • Impaired cognition
    • Slurred speech
    • Memory trouble
    • Paradoxical insomnia
    • Altered vision
    • Vertigo
    • Shaking or tremors
    • Respiratory depression
    • Nausea, constipation, diarrhea, vomiting, or abdominal cramps
    • Dry mouth
    • Loss of appetite

    High doses of any benzodiazepine, including Xanax, can cause an overdose.

    There are specific signs of a sedative overdose.

    • Slow reflexes
    • Mood swings
    • Hostile or erratic behavior
    • Euphoria or a high
    • Changes to breathing and heart rate

    If you notice someone exhibiting these symptoms, they may be overdosing on Xanax or another sedative. Call 911 immediately because they need emergency medical attention.

    Long-term harm is associated with ongoing Xanax abuse. Not only can constant intoxication on these drugs cause problems at work, school, or with family and friends, but Xanax significantly increases cognitive impairment, leading to problems with memory and judgment. This may become a chronic issue.

    The risk of motor vehicle crashes increases with ongoing addiction and abuse, which can lead to a physical injury that may not heal, such as a back injury or head injury, or damage to internal organs. Benzodiazepine abuse has also been associated with a 50 percent increased risk of hip fractures in older adults. A long-term study suggested that ongoing, high-dose abuse of Xanax or Valium can cause permanent brain damage.

    Overcoming Addiction Through Medically Supervised Detox and Rehabilitation

    Withdrawal from Xanax can range from uncomfortable to life-threatening.

    There are common withdrawal symptoms associated with the drug, including:

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    • Rebound anxiety and panic
    • Suicidal thoughts or actions
    • Difficulty sleeping, including insomnia
    • Blurry vision
    • Excessive sweating
    • Aggression
    • Depression
    • Seizures

    For the most part, though, withdrawal mimics the symptoms that Xanax was developed to treat, especially insomnia and panic. Experiencing these symptoms again can be highly uncomfortable for someone trying to stop Xanax abuse, and it can lead to relapse very quickly. It is important to stop taking Xanax – either because it has been abused or because the prescription is ending – with oversight from a physician or addiction treatment specialist.

    People who take Xanax consistently are not automatically going to develop an addiction to this drug, but many are at risk of developing physical dependence, which can cause withdrawal symptoms. When working closely with a prescribing physician, you will likely begin tapering off the drug, especially if you needed to take high doses at first or took Xanax for longer than two weeks. Studies have shown that people who took the drug regularly for three to six months did not have a problem stopping their prescription as long as a medical professional oversaw a tapering process to ease them off it.

    Some people who abuse Xanax may receive Valium as part of their withdrawal process. This medication acts on the brain longer than Xanax does, relieving cravings for the drug. Valium doses can then be tapered on a personalized schedule until the body no longer relies on the medication to feel normal.

    Once a medical detox has been completed, it is essential to enter a rehabilitation program with behavioral counseling, which can help you to recognize compulsive behaviors and develop better coping mechanisms. The best way to do this is through cognitive behavioral therapy (CBT) and related therapeutic approaches in both group and individual therapy.

    If You’re Suffering From Xanax Addiction, We Can Help

    If you or someone you know is addicted to Xanax, you’re not alone! Millions of people in the United Stated struggle with a substance use disorder each and every year. At Ocean Breeze Recovery, we understand how challenging it can be dealing with the financial, emotional, and physical difficulties that come along with addiction. That’s why we’ve optimized our addiction treatment program to be tailored to meet your individual needs.

    Our team of addiction professionals is standing by waiting for your call. We are available 24-7 and are ready to take your call and answer any questions you may have regarding your or your loved one’s Xanax addiction.

    Don't delay, addiction is a chronic and progressive disease that can result in numerous negative outcomes - including overdose and even death. Call Ocean Breeze Recovery at (844) 554-9279 now and get started on the road to recovery!

    SOURCES

    Managing Anxiety Disorders Can Be Difficult, But Help is Available. Xanax.com: Alprazolam Tablets. Retrieved August 2018 from https://www.xanax.com/

    (May 10, 2017). What is Xanax (Alprazolam)? Everyday Health. Retrieved August 2018 from https://www.everydayhealth.com/drugs/xanax

    (February 18, 2016). Benzodiazepine overdose deaths soared in recent years, study finds. CNN. Retrieved August 2018 from https://www.cnn.com/2016/02/18/health/benzodiazepine-sedative-overdose-death-increase/index.html

    Benzodiazepine Abuse. WebMD. Retrieved August 2018 from https://www.webmd.com/mental-health/addiction/benzodiazepine-abuse#1

    (October 29, 2013). Benzodiazepines. Center for Substance Abuse Research. Retrieved August 2018 from http://www.cesar.umd.edu/cesar/drugs/benzos.asp

    How Drugs Affect Neurotransmitters: Benzodiazepines. The Brain from Top to Bottom. Retrieved August 2018 from http://thebrain.mcgill.ca/flash/i/i_03/i_03_m/i_03_m_par/i_03_m_par_benzodiazepines.html#drogues

    (March 2011). XANAX. Food and Drug Administration (FDA). Retrieved August 2018 from https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018276s044,021434s006lbl.pdf

    (February 25, 2011). Hooked on benzodiazepines: GABAA receptor subtypes and addiction. HHS Public Access Author Manuscript. Retrieved August 2018 from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020178/.

    (September 19, 2015). Prescription drug abuse. Mayo Clinic. Retrieved August 2018 from https://www.mayoclinic.org/diseases-conditions/prescription-drug-abuse/symptoms-causes/syc-20376813.

    (December 20, 2016). Drugs Most Frequently Involved in Drug Overdose Deaths: United States, 2010-2014. Centers for Disease Control and Prevention (CDC). Retrieved August 2018 from https://www.cdc.gov/nchs/data/nvsr/nvsr65/nvsr65_10.pdf

    (March 4, 2016). Long-Term Use of Benzodiazepines: Issues and Challenges. Psychiatric News, the American Psychiatric Association (APA). Retrieved August 2018 from https://psychnews.psychiatryonline.org/doi/full/10.1176/appi.pn.2016.PP3a1.

    (December 18, 2014). Benzodiazepines in Combination with Opioid Pain Relievers or Alcohol: Greater Risk of More Serious ED Visit Outcomes. Substance Abuse and Mental Health Services Administration (SAMHSA), Drug Abuse Warning Network (DAWN) Report. Retrieved August 2018 from https://www.samhsa.gov/data/sites/default/files/DAWN-SR192-BenzoCombos-2014/DAWN-SR192-BenzoCombos-2014.pdf.

    (August 15, 2013). Risks Associated with Long-Term Benzodiazepine Use. American Family Physician (AAFP). Retrieved August 2018 from https://www.aafp.org/afp/2013/0815/p224.html.

    (November 18, 2010). Brain Damage from Benzodiazepines: The Troubling Facts, Risks, and History of Minor Tranquilizers. Psychology Today. Retrieved August 2018 from https://www.psychologytoday.com/us/blog/side-effects/201011/brain-damage-benzodiazepines-the-troubling-facts-risks-and-history-minor.